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Lynchburg Journal of Medical Science

Lynchburg Journal of Medical Science

Specialty

Primary Care, Hepatology

Advisor

John Morrison, MD. Karen Genco, PA-C. Lijia Paul, PA-C

Abstract

Importance: Hepatitis C is a disease that leads to many chronic extrahepatic conditions. The establishment of the connection between hepatitis C infection and diabetes mellitus may help to change the current practice protocol and better manage both conditions.

Objective: To investigate the relationship between hepatitis C and diabetes mellitus to establish a correlation to change clinical practice.

Evidence Review: a systematic review of English-language literature on Pub-Med published in the last five years to identify articles related to hepatitis C and diabetes mellitus in adults.

Conclusion and Relevance: Multiple pieces of researches support the linkage between hepatitis C infection and type 2 diabetes mellitus. In clinical practice, hepatitis C infection shall be eradicated with antiviral treatment to prevent the development of extrahepatic complications. A protocol of biannual HA1C evaluation in hepatitis C patients needs to be established to monitor the onset of insulin resistance and type 2 diabetes mellitus. Elevated HA1C will require prompt treatment initiation to prevent complications of diabetes.

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