Primary Care, Hepatology
John Morrison, MD. Karen Genco, PA-C. Lijia Paul, PA-C
Importance: Hepatitis C is a disease that leads to many chronic extrahepatic conditions. The establishment of the connection between hepatitis C infection and diabetes mellitus may help to change the current practice protocol and better manage both conditions.
Objective: To investigate the relationship between hepatitis C and diabetes mellitus to establish a correlation to change clinical practice.
Evidence Review: a systematic review of English-language literature on Pub-Med published in the last five years to identify articles related to hepatitis C and diabetes mellitus in adults.
Conclusion and Relevance: Multiple pieces of researches support the linkage between hepatitis C infection and type 2 diabetes mellitus. In clinical practice, hepatitis C infection shall be eradicated with antiviral treatment to prevent the development of extrahepatic complications. A protocol of biannual HA1C evaluation in hepatitis C patients needs to be established to monitor the onset of insulin resistance and type 2 diabetes mellitus. Elevated HA1C will require prompt treatment initiation to prevent complications of diabetes.
Yu J. Susceptibility to Type 2 Diabetes Mellitus in Hepatitis C Patients: A Systematic Review. University of Lynchburg DMSc Doctoral Project Assignment Repository. 2019; 1(1).
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