Lynchburg Journal of Medical Science

Lynchburg Journal of Medical Science




Dr. Thomas Colletti


Post-Traumatic Stress Disorder (PTSD) is a disabling psychiatric disorder common among military personnel and veterans. PTSD manifests after a potentially traumatic event. The disorder presents itself in a variety of ways, such as sleep disturbances, changes in cognition, mood and emotional changes, and with reduced social skills. Current medication therapy consists of anxiolytics and antidepressants which are often inefficient and have considerable side effects. Cognitive behavioral therapy is also utilized but is not effective for all participants.

There is an indication that Cannabidiol (CBD) has considerable potential as a treatment for multiple anxiety disorders, with the need for further study of chronic and therapeutic effects in relevant clinical populations. Studies that involve animal models of anxiety and also, healthy volunteers suggest an anxiolytic-like effect of CBD.

The goal of this review is to highlight the potential of CBD as a treatment for disorders involving debilitating recall of aversive memories, the anxiety associated with these memories and as an adjunctive treatment for PTSD.


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