Lynchburg Journal of Medical Science

Lynchburg Journal of Medical Science


Critical Care


Dr. Thomas Colletti


The issue of appropriate management hyperglycemia in critically ill patients is neither new or uncommon. However, this has evolved over the past 10 years and the data often appears conflicting. The purpose of this review paper is to evaluate the effect of tight glucose control on clinical outcome in critically ill patients. Tight glycemic control (80-120 mg/dl +/- 10) is also referred to in the literature as Intensive Insulin Therapy (IIT). By evaluating both older and more recent literature, it is expected that the review will demonstrate that there is a direct link between blood glucose (BG) levels and prognosis (morbidity and mortality) in the critically ill patient.


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