University of Lynchburg DMSc Doctoral Project Assignment Repository
Specialty
Orthopedic Surgery
Advisor
Dr. Elyse Watkins
Abstract
- Orthopedic procedures involving metallic implants are increasingly common with projection in future growth.
- There remains some debate regarding the local and systemic impact of metal induced allergic reactions following implantation of orthopedic instrumentation.
- To date, there is no accepted universal standard for a valid, cost-effective diagnostic approach to detect metal hypersensitivity in patients scheduled to undergo implantation of a prosthetic device orwho have already undergone such a procedure.
- Inpatients who are scheduled for a surgery involving a metallic implant who are known to have allergic reactions to worn or implanted metal, research supports a role for skin patch testing with possible follow up lymphocyte transformation testing as a safe and cost-effective way to improve patient outcomes and possibly reduce the need for future revision surgery.
- A review of the literature regarding the incidence and clinical significance of metal hypersensitivity and to help understand the role for testing in the prevention of allergic reactions to orthopedic implants.
Recommended Citation
Peterkin BA, Reiter MF, Drzala MR. The Significance of Metal Sensitivity Testing in Instrumented Orthopedic Surgery. University of Lynchburg DMSc Doctoral Project Assignment Repository. 2019; 1(3).
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