Lynchburg Journal of Medical Science

Lynchburg Journal of Medical Science





Introduction: Sickle cell disease patients have increased the risk of complications during pregnancy as well as morbidity and mortality. The pathophysiology of the disease leads to complications affecting both the mother and the baby. Transfusion is the only treatment available for pregnant sickle cell patients.

Discussion: There are two types of transfusions commonly used, prophylactic transfusions and symptomatic transfusions. While the benefits for the symptomatic transfusions are clear, as they resolve acute crises, prophylactic transfusions may also have a place for prevention.

Conclusion: Although there seems to be some benefit in prophylactic and symptomatic transfusions, more studies need to be conducted to determine the short and long term outcomes in the mothers and children.

Keywords: Sickle Cell Disease, Pregnancy, Transfusion


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