An Overview of Oral Mucositis in Pediatric Bone Marrow Transplant Patients

Authors

Lauren K. Adams, Johns Hopkins All Children's HospitalFollow

Specialty

Pediatric Bone Marrow Transplant

Advisor

Dr. Nancy Reid

Abstract

ABSTRACT

Purpose: The purpose of this article is to provide physician assistants with a review of the signs, symptoms, diagnosis, management, and preventative measures for mucositis in the pediatric bone marrow transplant population.

Method: A PubMed literature search was conducted with search terms Palifermin, pediatric mucositis, oral mucositis, mucositis management, Palifermin use in pediatrics.Thirty-three articles were retrieved and will serve as the basis for this clinical review.

Results:Oral mucositis increases morbidity and mortality in the pediatric bone marrow transplant population. There is a lack of evidence-based research to demonstrate the utility of methods to prevent mucositis in the pediatric population.

Conclusion: More prospective and retrospective information is needed to determine the most effective ways to prevent and manage mucositis.

Keywords: pediatrics, mucositis, Palifermin, hematopoietic cell transplant, leukemia, total body irradiation, Palifermin.

Recommended Citation

Adams LK. An Overview of Oral Mucositis in Pediatric Bone Marrow Transplant Patients. University of Lynchburg DMSc Doctoral Project Assignment Repository. 2019; 1(4).