University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository




Anyssa Garza



The purpose of this literature review is to provide evidence-based medicine on the recommended timing of the test-of-cure (TOC) in a pregnant female to prevent maternal- fetal transmission. I used PubMed clinical queries to research my selected topic. Keywords used were Chlamydia trachomatis(CT), pregnancy, and TOC. I then reviewed ten articles and selected six articles to assist in my journal article. Filters chosen were publication dates of five years, human species, and free full text. Through literature analysis and research, the recommended timing of the TOC for CT in pregnancy is to be performed four weeks after diagnosis. Treating any type of sexually transmitted infections (STI) in pregnancy is necessary to prevent maternal-fetal transmission. The question is, at what time during gestation is it recommended to treat? Will it be feasible to treat one month after diagnosis or at thirty-five weeks gestation? Following single dose treatment for chlamydia, pregnant women should test negative by thirty days post treatment. Practitioners should collect a TOC in pregnant women no earlier than one month.1

Keywords: Chlamydia trachomatis, Pregnancy, Test-of-Cure


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