Asthma is a common chronic disease in children and adults. In 2016 there were more than 20 million adults and 6 million children with asthma in the United States.1 Poorly controlled asthma contributes to poor disease outcome, decreased quality of life and school/work absenteeism. Once asthma is well controlled the most recent asthma guidelines, published in 2007, recommend step down therapy. The FDA had advised limiting use of long-acting beta-agonists (LABA) due to safety concerns.2,3 The most recent research released on LABA use demonstrates the safety of LABA when used in combination with inhaled corticosteroids (ICS) and resulted in the FDA lifting the black box warning from LABA containing medications.4 This review article will cover currently accepted guidelines for the management of chronic asthma and approaches to step down therapy.
Rollins, Heather M.
"Asthma: Chronic Management and Step-down Therapy Update,"
Lynchburg Journal of Medical Science: Vol. 1
, Article 58.
Available at: https://digitalshowcase.lynchburg.edu/dmscjournal/vol1/iss4/58
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