University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository


Dr. Nancy Reid



  • Objectives: To review bacterial vaginosis and discuss the possible use of probiotics for the prevention of recurrent bacterial vaginosis
  • Methods: A literature search was performed using the PubMed, Science Direct and Cochrane database with search terms including bacterial vaginosis, prevention, and probiotics. The filters used include “within the last ten years” and “clinical trials”.
  • Results: A total of 15 relevant articles were found
  • Conclusions: Multiple Randomized Controlled Trials (RCTs) have shown that the use of oral or vaginal probiotics can be effective at both treatment and prevention of recurrent of bacterial vaginosis. Available RCTs that focus on the treatment of BV often combine current treatment guidelines of oral antibiotics with probiotic supplements, and prevention studies typically use prolonged treatment with probiotics after antibiotic therapy. However, because of the variety of treatments among available studies further research should be done to determine the adequate dose, specific probiotic, optimal duration and route of administration with or without antibiotics.
  • Keywords: Bacterial Vaginosis, Prevention, Recurrent, Probiotics.


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