Dr. Nancy Reid
Purpose: The purpose of this article is to review the factors that affect the flare-up of gout in the
Method: The following sites were used to conduct research: PubMed, Journal of Medicine,
Elsevier Science Direct, American College of Rheumatology, CrossMark, BMJ, Arthritis
Research Therapy. Sixteen pertinent articles were retrieved, and they served as the basis for
this clinical review.
Results: Patient education and counseling adjunct with therapy are under investigation to
improve gout treatment often showing encouraging results.¹
Conclusion: A large proportion of patients with gout also have comorbid diseases. Obesity and
hypertension were common comorbidities among patients who developed flares. Additionally,
several lifestyle factors such as obesity and high alcohol intake were related to the risk of gout
flares. Moreover, some of these underlying conditions that could also impact treatment which
also makes them modifiable risk factors for flares. Further lifestyle changes can prevent the
flare-up and worsen of gout conditions.¹
Keywords: gout, hyperuricemia, flares, lifestyle modification, alcohol, high fructose-sweetened drinks.
Nguyen HH. Factors Affecting Gout Flare-Up. University of Lynchburg DMSc Doctoral Project Assignment Repository. 2020; 2(2).
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