Lilia Yakubov, BSN; Lourdes Pelaez-Echevarria, DO, FACOS
Objective: To analyze the available data and determine whether preoperative oral carbohydrate loading (CHO), an important part of the Enhanced Recovery After Surgery (ERAS) protocol, can lower post-surgery complications related to insulin resistance when compared to fasting in elective abdominal surgery patients.
Methods: All studies through PubMed and Google Scholar were analyzed and sorted for their relevance. Studies prior to 2014 were excluded. The studies with diabetes mellitus were excluded. Only studies with adult participants and open access were included.
Results: Overall, two randomized control trials and a cross-sectional study were chosen for this paper due to their relevance. Two studies demonstrated CHO increased insulin sensitivity and patient comfort by reducing anxiety, hunger, and thirst postoperatively. One study revealed a decrease in insulin sensitivity after major abdominal surgery, however, pre-op CHO or obese vs non-obese status of participants did not have an impact on insulin sensitivity.
Conclusion: Administration of preoperative CHO increases insulin sensitivity and is probably safe with a better influence on other perioperative clinical outcomes.
Shahani D. Preoperative Oral Carbohydrate Loading in Elective Abdominal Surgery. University of Lynchburg DMSc Doctoral Project Assignment Repository. 2020; 2(2).
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