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Lynchburg Journal of Medical Science

Lynchburg Journal of Medical Science

Specialty

DMSc

Advisor

Dr. E Watkins

Abstract

Vitiligo is a progressive skin disorder in which melanocytes no longer produce pigment. Depigmented white macular patches may present itself on various parts of the body. The exact etiology is unknown however, autoimmune destruction of melanocytes is widely used and studied. Oxidative stress also plays a vital role in the destruction of melanocytes leading to loss of pigmentation. Treatment modalities for vitiligo remain the same. The role of antioxidants, such as Vitamin B12 and Folic Acid, has emerged as an interest of new therapy. Reported data thus far is encouraging, however more extensive studies is needed for validation and to establish a positive correlation.

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