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University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository

Acute Ventricular Septal Defect: Recognition and management in the ERa of Reperfusion

Specialty

Cardiovascular and Thoracic Surgery

Advisor

Elyse Watkins, DHSc, PA-C

Abstract

ABSTRACT:

Cardiovascular disease remains the number one cause of death among men and women in the United States (US) and the world. Millions of patients suffer myocardial infarction (MI) each year and a small but significant number of these patients will develop an acute ventricular septal defect (VSD) as a complication of their MI. This complication has seen a ten-fold decrease in the era of reperfusion but mortality remains high despite advanced mechanical support, surgical techniques and percutaneous treatment options. Early surgical and percutaneous treatment is associated with higher mortality making early, aggressive supportive medical management critical to allow for delayed, definitive treatment and the opportunity for survival.

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