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University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository

Specialty

DERMATOLOGY

Advisor

Dr. Elyse Watkins, DHSc, PA-C, DFAAPA

Abstract

Keloid represents highly hyperproliferative pathological skin problems manifested as aberrant remodeling of the skin after or during wound healing. The cause of keloids is not well understood, but keloids occur in genetically predisposed individuals in addition to growth factors and cytokines playing major roles. Keloid disfigurement negatively impacts a patient’s well being physically and psychologically. Inquiries on keloid emergence have been performed for years and have driven to plenty of restorative procedures to lessen the burden of unreasonable disfiguring aspects of the condition in attempts to improve patient’s self-comfort. So far, for the most part, restorative attempts have shown unequivocally dissatisfying results, indebted to the inadequate insight of the intricate process of wound scarring. There is no general agreement for a standard treatment approach for keloid, nonetheless, intralesional infusions of triamcinolone acetonide alone, or in combinations, may be a successful treatment choice for the condition. As knowledge of the keloid disease process increases, a standard therapy will be formulated in the nearer future.

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