Lynchburg Journal of Medical Science

Lynchburg Journal of Medical Science


Family Medicine


Dr. Laura Witte



Purpose: The purpose of this article is to review the treatment of hypertriglyceridemia in adults, comparing the effectiveness of fenofibrate with omega-three fatty acids in reducing serum triglyceride levels

Methods: A PubMed and Medline literature search were performed with search terms: hypertriglyceridemia, treatment, fenofibrate, omega-three fatty acids. Eleven pertinent articles were retrieved, and they serve as the basis for this clinical review.

Results: A variety of evidence-based research on the treatment of hypertriglyceridemia using either fenofibrate and omega-3 fatty acids were reviewed, and result was fenofibrate was more effective in lowering triglycerides levels than omega-three fatty acids.

Conclusions. Hypertriglyceridemia is associated with heart disease. Currently, the treatment of hypertriglyceridemia using fenofibrate is more effective in lowering the triglycerides level than omega-three fatty acids. Further research is needed in the treatment of hypertriglyceridemia


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