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University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository

Specialty

Dermatology

Advisor

Nancy Reid, MHA, DHSc, PA-C, DFAAPA

Abstract

Psoriasis vulgaris is a common inflammatory disease of adults and children. Affected patients are often incorrectly diagnosed, undertreated, or not treated at all. The condition is correlated to social isolation, anxiety and depression, and can negatively influence personal relationships and employment status. Psoriasis has a significant psychological and socioeconomic impact that can persist throughout a patient’s life. Skin involvement is the most distinguished demonstration of this disease; understanding that psoriasis is a chronic, multisystem inflammatory disease is essential to enhance treatment. The relapsing course of psoriasis negatively affects the quality of life. Patients with mild-to-moderate psoriasis can control the disease primarily with topical medications or phototherapy. Used as monotherapy or combined with phototherapy, topical medication can be inadequate for patients with moderate-to-severe psoriasis. Biologic agents used as monotherapy or combined with topical or systemic medications, offer treatment options with many benefits compared to risks in the treatment of psoriasis vulgaris.

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