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University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository

Specialty

Nephrology

Advisor

Dr. Nancy Reid, DHSc

Abstract

Hepatitis C virus (HCV) and chronic kidney disease (CKD) often co-exist due to their high incidence rates and often similar patient demographics. HCV diagnosis in the CKD patient will hasten progression of kidney failure, therefore it is imperative to treat HCV once the diagnosis is recognized. Initially, medications used to treat HCV were not tested in all stages of CKD; however, recent studies have included CKD patients in stages G1 to G5. The most recent classes of HCV medications are safe and effective in all stages of CKD. While there is little debate regarding treatment of the non-dialysis CKD patient with HCV, treatment of the dialysis patient is less absolute due to questions of transplant and expected long-term survival.

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