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Lynchburg Journal of Medical Science

Lynchburg Journal of Medical Science

Specialty

Emergency Medicine

Advisor

Nancy, Reid, DHSc, PA-C

Abstract

Severe sepsis and septic shock are common conditions in various clinical settings. Since mortality rates can be as high as 60 percent, rapid recognition and goal-directed therapy leads to improved survival. While much information about the pathophysiology of the disease and ways to treat it are known, recent updated international Surviving Sepsis Campaign (SSC) guidelines do not provide a concrete recommendation whether crystalloids or colloids should be administered alone or in a combination to restore hemodynamic endpoints and reduce mortality in a more timely and effective manner. This review spotlights potential new ways to manage a septic patient with a fluid combination therapy.

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