University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository


Orthopedic Surgery


Dr. Nancy Reid, MHA, DHSc, PA-C, DFAAPA


ABSTRACT: Purpose: The purpose of this article is to review the treatment of non-surgical knee osteoarthritis (OA) with intra-articular (IA) corticosteroid (CS) and hyaluronic acid (HA).

Method: A PubMed literature search was conducted with search terms knee osteoarthritis, corticosteroid, and hyaluronic acid. Twenty-four peer-reviewed articles were retrieved, and they serve as the basis for this clinical review.

Results: IA HA and IA CS benefit similarly with regard to improvement in knee function.

IA HA may benefit patients with knee OA for a longer period of time. IA HA and IA CS are considered safe.

Conclusion: A major cause of disability in adults is knee OA, which causes joint pain and functional limitation. IA therapies for symptomatic control are preferred over oral medications due to low risk of side effects. IA CS and IA HA have been recommended for symptomatic control. With review of the literature, IA HA and IA CS are both safe and efficacious treatments for pain control in patients with knee OA. Key words: Knee Osteoarthritis, Corticosteroid, Hyaluronic Acid.


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