University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository


Emergency Medicine


Dr Watkins



Purpose: This article reviews the current methods of diagnosing and subsequent management of Infective Endocarditis (IE). The aim is to reduce hospital stay, mortality and obtain favorable outcomes.

Method: A PubMed literature search with search terms Infective Endocarditis, Antibiotics, Diagnosis, and Complications was conducted. Eighteen pertinent articles were used as the basis for this clinical review.

Results: Despite advances in medical therapies, the early diagnosis of Infective Endocarditis is still a challenge. Recognizing the many presentations of the disease process is essential in effectively treating and minimizing its complications.

Conclusion: The complications of Infective Endocarditis affect multiple organ systems. Cardiac – related and neurological complications are some of the most seen complications. These complications are associated with a significant clinical impact secondary to increased mortality and morbidity. Additionally, they have economic impacts due to extended hospitalization and medical therapeutic cost. Prompt diagnosis of Infective Endocarditis despite its variable presentation is key to the successful management of the disease process. The overall goal is to reduce hospital stay length, associated cost, and the current high mortality rate associated with endocarditis.

Keywords: Infective Endocarditis, Valvular heart disease, Surgical Intervention, Antibiotics prophylaxis, Diagnosis.


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