Lynchburg Journal of Medical Science
Dr. Tom Colletti, DHSc, PA-C, DFAAPA
Introduction: The purpose of this article is to review the role of the gut-lung axis and the gut microbiome in viral immunity to COVID-19 in SARS-CoV-2 positive children presenting with gastrointestinal (GI) symptoms.
Methodology: The research aim was attained through a review that provides knowledge on the pediatric COVID-19 with GI symptoms from the research field published between 2019-2021. The review includes scientific data addressing the gut-lung axis and the gut microbiome in viral immunity to COVID-19 in positive children presenting with gastrointestinal symptoms (GI) using publicly available peer-reviewed papers found on PubMed.
Results: Evidence suggest that the gut microbiota composition is associated with the immune response to COVID-19. SARS-CoV-2 RNA persists longer in fecal samples than in oropharyngeal samples.
Discussion: Data is still evolving surrounding the transmission rate of COVID-19 by children. Further understanding of the relationship between SARS-CoV-2 and the role of gut microbiota is essential to prevent transmission.
Keywords: pediatric COVID-19, SARS-CoV-2, gut-lung axis, microbiome, gastrointestinal symptoms
Armendariz Martinez L. The Gut-Lung Axis in Pediatric COVID-19: Possible Link and Implications. Lynchburg Journal of Medical Science. 2021; 3(4).
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