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University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository

Specialty

Trauma Surgery

Advisor

Dr .Tom Colletti, DHSc, PA-C, DFAAPA

Abstract

Venous thromboembolism (VTE), which comprises deep vein thrombosis (DVT) and pulmonary embolism (PE), is a potentially life-threatening complication that affects severely injured patients worldwide. Although prevention and early recognition can reduce mortality, the occurrence of post-traumatic VTE is contributed to significant long-term morbidity. Prevention of VTE includes mobilization, mechanical and pharmacologic prophylaxis, and inferior vena cava (IVC) filters, and is considered the standard of care for trauma patients. Despite extensive literature discussing strategies for the prevention of VTE, level I evidence to guide practice remains limited. The purpose of this article is to review the pathophysiology, risk factors, clinical presentation, diagnosis, and treatment, as well as recommended prevention strategies for post-traumatic VTE to increase awareness and understanding of this high-risk complication.

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