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Lynchburg Journal of Medical Science

Lynchburg Journal of Medical Science

Specialty

Physical medicine and rehabilitation

Advisor

Dr. Tom Colletti, DHSc, PA-C, DFAAPA

Abstract

Purpose:

This article aims to review the clinical presentation of Fibrodysplasia Ossificans Progressiva (FOP), its basic science background management, and to emphasize the characteristic congenital malformation of the great toe to help increase awareness of FOP and to highlight the importance of its early diagnoses.

Method:

A PubMed literature search was conducted with the search terms fibrodysplasia ossificans progressiva. Ten pertinent articles were retrieved and served as the basis for this clinical review.

Results:

Most patients diagnosed with classic FOP are born with deformed great toes. The early recognition of this malformation can aid clinicians to identify and promptly diagnose FOP to avoid unnecessary medical procedures resulting in mismanagement that can further trigger excessive bone formation outside the skeletal system.

Conclusion:

Early identification of FOP is essential to avoid iatrogenic harm and unnecessary medical procedures such as surgeries, dental blocks, and biopsies.

Keywords:

Heterotrophic ossification, Osteochondrogenesis, Degenerative joint disease, Stoneman syndrome

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