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Lynchburg Journal of Medical Science

Lynchburg Journal of Medical Science

Specialty

Dermatology

Advisor

Dr. Elyse Watkins

Abstract

ABSTRACT

Purpose: The purpose of this article is to review the systemic nature of psoriasis, which causes an overactive immune system that can lead to cardiovascular disease risk factors.

Method: A PubMed literature search was conducted with the search terms “psoriasis and cardiovascular disease”. The search was refined to full-text articles published within the last five years, with the article type including meta-analysis, randomized controlled trials, and systematic reviews. The search resulted in a total of 34 articles, 14 of which were most pertinent.

Results: Evidence shows psoriasis patients have an increased risk of cardiovascular disease risk factors.

Conclusion: Patients with psoriasis have an increased prevalence of cardiovascular disease and cardiovascular risk factors. Cardiovascular disease risk factors consist of atherosclerosis, diabetes, obesity, dyslipidemia, hypertension, and metabolic syndrome. These cardiovascular disease risk factors can lead to major adverse cardiovascular events (MACE) and increased mortality.

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