Lynchburg Journal of Medical Science

Lynchburg Journal of Medical Science


Family Medicine


Dr T. Colletti



The aging of the global population has seen an increase in Alzheimer's Disease (AD) diagnosis. AD is the most common cause of dementia worldwide, with the prevalence continuing to grow in part because of the aging world population. Considering the disease mechanism of Alzheimer's disease, there is an effort to establish preventive treatments. Vascular changes of Alzheimer's are due to neurofibrillary tangles depriving the brain of essential nutrients compromising brain cell function. Ginkgo Biloba Extract (GBE) exerts its effect on the circulatory causes of Alzheimer's disease. The social consequences are the estrangement of sufferers, reduced social interaction, and gradual professional isolation. The primary characteristics are the erosion of memory cognition and disorientation, resulting from losing neuronal structure and function in different brain parts. Although Ginkgo Biloba Extract (GBE) has seen widespread use as a dietary supplement to improve memory, its efficacy in treating and preventing Alzheimer's Disease remains controversial. This review will investigate progress, the potential use of GBE, and its efficacy in preventing AD. The development of therapeutic strategies to treat AD requires a basic understanding of the neurodegenerative process and the neuroprotective effects of herbal GBE.

A Google Scholar and PubMed literature search with search terms Ginkgo Biloba, Alzheimer’s disease dementia, and vascular dementia yielded several pertinent articles providing a foundation for this clinical review.


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