University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository




Dr. Larry Herman, DMSc, MPA, PA-C, DFAAPA



Purpose: This review article will enable early recognition of symptoms to minimize the severity of neurological deficits associated with white cord syndrome.

Method: A PubMed literature search was conducted between June 2021 and November 2021 using the search terms “spinal cord injury, white cord syndrome, reperfusion injury, and steroid use in spinal cord injury.” Twenty-nine relevant articles were selected and used for this clinical review.

Results: White cord syndrome a reperfusion injury of the spinal cord following decompressive surgery. Rapid expansion and abrupt reperfusion in the presence of oxidative free-radicals can lead to an ischemic injury and permanent disability.

Conclusion: White cord syndrome is a rare but devastating complication of spinal cord decompression. Early recognition of clinical symptoms and immediate intervention is pertinent to prevent or alleviate permanent neurological dysfunction.

Keywords: Spinal cord injury, white cord syndrome, spinal cord reperfusion injury

Disclosures: I have no disclosures to report


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