University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository


Internal Medicine


Dr. Larry Herman, DMSc, MPA, PA-C, DFAAPA



Purpose: The purpose of this article is to review Helicobacter pylori infection being the underlying cause of non-severe idiopathic immune thrombocytopenia.

Design: A narrative review of low platelet count disorders.

Method: A PubMed literature search was conducted with search terms “Helicobacter pylori”, “thrombocytopenia”, “immune thrombocytopenia”, and “low platelets disorder”. Then by using the advanced search link “ITP” and “H. pylori” were typed into the search builder. The best-selected articles were then retrieved and served as the basis for this clinical review.

Results: The treatment of underlying Helicobacter pylori infection results in the increase of platelet levels.

Conclusion: Eradication therapy of H. pylori is inexpensive and by assessing and treating underlying H. pylori infection, platelet numbers increase and often cure ITP. It is also advantageous in avoiding long-term corticosteroid or immunosuppressive treatment for those who respond positively, thus reducing overall healthcare costs.

Keywords: Idiopathic thrombocytopenia, Immune thrombocytopenia, Helicobacter pylori.


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