Lynchburg Journal of Medical Science

Lynchburg Journal of Medical Science


Emergency Medicine


Dr. Tom Colletti


Cannabinoid hyperemesis syndrome is a relatively new diagnosis and not easily recognized by emergency clinicians due to its similarity to many gastrointestinal disorders. The increased prevalence of cannabis use in states with medical and recreational cannabis legalization reflects a higher incidence of cannabis-related illnesses. Cannabinoid hyperemesis symptoms can be challenging to diagnose and treat, leading to expensive diagnostic interventions, prolonged emergency room stay, unnecessary surgeries, and preventable inpatient admissions. This article is a clinical review of the symptoms, pathophysiology, treatment, and prevention of cannabinoid hyperemesis syndrome and rapid recognition by clinicians. Cannabis cessation is the only cure for CHS.


Available when accessing via a campus IP address or logged in with a University of Lynchburg email address.

Off-campus users can also use 'Off-campus Download' button above for access.