University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository


Hospital Medicine


Dr. Tom Colletti, DHSc, PA-C, DFAAPA



Hyponatremia is the most common electrolyte disorder in hospitalized cancer patients. This disorder can prolong hospitalization, and worsen patient performance status and quality of life. Severe and acute hyponatremia is associated with increased mortality risk, and there is evidence that moderate or even mild chronic hyponatremia may also increase the risk of death. Understanding how to correctly diagnose and treat hyponatremia is crucial to the patient's survival. Incorrect rapid correction can lead to catastrophic adverse neurological effects. An evidence-based review of hyponatremia in cancer patients can help guide providers to correct sodium levels given that treating hyponatremia is associated with reducing overall mortality.


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