Lynchburg Journal of Medical Science

Lynchburg Journal of Medical Science




Dr. Thomas Colletti


Alopecia areata (AA) is a common auto-immune condition which results in chronic and recurrent non-scarring patchy hair loss. A continuum of conditions exists from AA to alopecia totalis (AT) and alopecia universalis (AU). Although AA is typically a self-limited condition some cases may last for months or years and a minority are indefinite. The psychological and social impacts of the condition can be substantial. To date there are no medications approved by the Food and Drug Administration (FDA) for the treatment of AA and its variants. Currently available treatments are wide ranging and highly variable in their effectiveness. Janus kinase (JAK) inhibitors offer a promising potential treatment for AA.


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