University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository




Elyse Watkins, DHSc, PA-C, DFAAPA, NCMP


Purpose: The purpose of this article is to review the use of calcitonin gene-related peptide inhibitors in the management of migraine patients.

Method: A PubMed literature search was conducted with search terms migraine, CGRP, and prevalence, and eleven articles were deemed appropriate for this manuscript. One publication written by an expert in the field was also utilized for background information.

Results: Calcitonin gene-related peptide inhibitors are a safe and effective option for patients with migraine headaches.

Conclusion: Migraine headaches are a debilitating condition affecting patients throughout their lives, with an increase in prevalence during their most productive years. Previous preventative treatments have been plagued with minimal efficacy and unsatisfactory side effect profiles. The approval of both preventive and abortive CGRP inhibitors has had profound impacts on migraine management and quality of life for the migraine patient.


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