Lynchburg Journal of Medical Science
Dr. Laura Witte
Whipple’s disease (WD) is a chronic infectious disease that is fatal if left untreated and may result in irreversible damage if treatment is delayed. A study published in 2019 suggests that WD is more prevalent than originally thought making improved awareness among clinicians of vital importance. Due to the high variability of presenting signs and symptoms, which may be encountered across multiple specialties, establishing the diagnosis can be challenging. While treatment is highly effective for inducing remission, recurrence is possible making long-term monitoring an essential part of the management plan. This article describes WD, its proposed pathophysiology, common presentations, methods of diagnosis, and recommendations for management.
Garrison H. Whipple's disease: No longer one in a million?. Lynchburg Journal of Medical Science. 2023; 5(1).
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