Lynchburg Journal of Medical Science

Lynchburg Journal of Medical Science


Addiction Medicine


Dr. Tom Colletti


Alcohol use disorder (AUD) is a DSM-5 diagnosis defined as a dependence on alcohol that leads to continued use even when it causes harm or distress. AUD is the most common substance use disorder in the United States and is often undertreated. One of the ways healthcare providers can help those who suffer from AUD in their journey to recovery is through medication-assisted therapy (MAT). MAT involves using medications in conjunction with psychosocial interventions to treat substance use disorders, including AUD. The United States Food and Drug Administration (FDA) has approved three medications for treating AUD. These medications work by either reducing the physiological cravings for alcohol or by creating undesirable symptoms when alcohol is consumed. This article provides an overview of MAT for AUD and the current FDA-approved medications used.


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