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University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository

Specialty

Emergency Medicine

Advisor

Dr. Elyse Watkins

Abstract

Antibiotic resistance is a growing problem that will require innovative solutions in the very near future. Clinicians are in a position that will have them navigating the impending lapse in a previously robust sphere of treatment options. This review discusses the background and development of antibiotics, the emergence and trajectory of antibiotic resistance, and characterizes the use of phage therapy in the treatment of antibiotic-resistant infections. Comparing the rate of successful treatment of multi-drug resistant infections with phages versus a powerful course of one or more antibiotics, phage therapy is emerging as a viable alternative. Since the development of new and effective antibiotic classes has stagnated, this treatment modality is a promising possibility for a looming crisis.

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