University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository


Obstetrics and Gynecology


Dr.Walton,Mary DMSc



This review will discuss the pharmacological management and dosing of common psychiatric disorders during pregnancy and postpartum and the risks of no treatment. Psychiatric disorders during pregnancy are common. Approximately 25% of pregnant women have a psychiatric diagnosis, including major depression, generalized anxiety disorder, bipolar disorder, and schizophrenia. Adverse maternal, fetal, and pregnancy outcomes, the risk of congenital anomalies with psychotropics, and the risks of untreated disorders are outlined. Abrupt medication discontinuation in patients with psychiatric conditions is associated with an increased risk of recurrence and relapse during pregnancy. The physiologic changes during pregnancy and postpartum may alter the pharmacokinetics of psychotropics, leading to subtherapeutic drug levels. A multidisciplinary approach providing early screening, diagnosis and treatment are essential to decrease the morbidity and mortality of psychiatric disorders during pregnancy. This review will guide clinicians in making evidence-based treatment decisions regarding the pharmacological management of psychiatric disorders during pregnancy and postpartum.


Available when accessing via a campus IP address or logged in with a University of Lynchburg email address.

Off-campus users can also use 'Off-campus Download' button above for access.