University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository


Primary Care



Long COVID is a relatively new syndrome of uncertain chronicity. The syndrome presents in multiple fashions with one or more coronavirus-2 (COVID-19) symptoms persisting, reactivating, or beginning 12 weeks or more after the initial COVID-19 infection. Increasing survival rates from COVID-19 mean a growing number of patients at risk for developing long COVID. With more than 93 million confirmed COVID-19 cases in the United States by September 9, 2022, the likelihood of a primary care clinician treating patients with long COVID is significant. Clinicians must be poised to identify, treat and recognize when to refer care for their long COVID patients. This article reviews the etiology, complications, putative pathophysiology, diagnosis, differentials, treatments, and future direction of long COVID in managing primary care patients with previously mild-moderate COVID-19 illnesses.


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