University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository




Nasser El-Okdi, MD


Background: Dyschromia is defined as a set of pigment disorders, most commonly exhibited as melasma, post-inflammatory hyperpigmentation, and solar lentigo, which are generally either inflammatory/allergic in response or hormonal or solar in origin. The condition is more seen in patients with skin of color.

Objective: To identify the safety and efficacy of using laser therapies for the treatment of dyschromia in patients with skin of color.

Methods: Searched the PubMed and MEDLINE databases, using select keywords to yield 197 articles about dyschromia and the user of laser technology. Of the 197 articles, only 27 articles were relevant and were selected for review.

Results: A review of clinical safety and efficacy of the Q-switched nanosecond lasers, the 755nm picosecond alexandrite laser, and the 1,097nm nonablative fractional thulium laser has proven that cutaneous laser therapy is advancing for not only Fitzpatrick skin types I-III but also for darker skin types, such as Fitzpatrick skin types III-VI in the treatment of dyschromia and associated pigment disorders.


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