University of Lynchburg DMSc Doctoral Project Assignment Repository

University of Lynchburg DMSc Doctoral Project Assignment Repository


Sports Medicine


Dr. Dipu Patel


Attention-Deficit/Hyperactivity Disorder (ADHD) causes significant functional impairment and financial burden on the individual and society, respectively. Concerns regarding the safety of psychostimulant medication and patient non-adherence issues secondary to side-effect profiles have led to the exploration of alternative treatments. An imbalance in the gut microbiota composition is a proposed contributor to the pathophysiology of neuropsychiatric disorders via the bidirectional microbiota-gut-brain axis. Patients with ADHD have been shown to have a different gut microbiota composition compared to controls and exercise has demonstrated executive function and motor skill improvement in this population. The purpose of this review article is to assess the efficacy of exercise as an ADHD therapy through the modulation of the gut microbiota.


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