Lynchburg Journal of Medical Science

Lynchburg Journal of Medical Science


Aesthetic Medicine


Elyse Watkins, DHSc, PA-C, DFAAPA



Depression continues to rank among the most prevalent medical conditions globally. Despite the availability of numerous treatments for depression, there is still a large population that does not achieve remission through traditional antidepressants. Recent research has shown that injecting botulinum toxin type A (BTX-A) into the glabellar muscles significantly reduced depressive symptoms. Because BTX-A is widely used and has a well-established safety profile, medical providers should be aware of its promising benefits for depression. Additional research is required to ascertain the precise dosage of BTX-A, whether it be monotherapy or adjunct therapy, and to investigate the underlying mechanism.


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