Lynchburg Journal of Medical Science

Lynchburg Journal of Medical Science


Emergency Medicine


Elyse Watkins, DHSc, PA-C, DFAAPA, NCMP


Gut fermentation syndrome, or Auto-Brewery Syndrome, is a condition where endogenous fermentation by fungi or bacteria produces ethanol in the gastrointestinal system. Signs and symptoms of Auto-Brewery Syndrome mimic alcohol intoxication without alcohol intake. It is essential to rule out other etiologies before diagnosing Auto-Brewery Syndrome. Elevated blood or breath ethanol levels after a carbohydrate challenge confirm the diagnosis. Management of Auto-Brewery Syndrome includes diet modification of low carbohydrate and high protein in addition to drug therapy.


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