Lynchburg Journal of Medical Science
Elyse Watkins, DHSc, PA-C, DFAAPA, NCMP
Gut fermentation syndrome, or Auto-Brewery Syndrome, is a condition where endogenous fermentation by fungi or bacteria produces ethanol in the gastrointestinal system. Signs and symptoms of Auto-Brewery Syndrome mimic alcohol intoxication without alcohol intake. It is essential to rule out other etiologies before diagnosing Auto-Brewery Syndrome. Elevated blood or breath ethanol levels after a carbohydrate challenge confirm the diagnosis. Management of Auto-Brewery Syndrome includes diet modification of low carbohydrate and high protein in addition to drug therapy.
Samutsakorn DK. The intoxicated man who did not drink: a case of Auto-Brewery Syndrome. Lynchburg Journal of Medical Science. 2023; 5(2).
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