University of Lynchburg DMSc Doctoral Project Assignment Repository
Abstract
Leptospirosis is the most common zoonosis worldwide. The pathogenic leptospira is a spirochete that can cause human kidney failure and death. The presentation of symptoms is subtle and can be mistaken as a flu-like illness, with abrupt fever being the most common symptom. The incubation period for the spirochetes is up to 30 days, with an average of 10 days. Symptoms can vary, making the diagnosis difficult. A history of exposure to freshwater or soil that Leptospira contaminated is helpful in diagnosing. Successful treatment of the spirochete infection can be accomplished with broad-spectrum antibiotics. This article reviews the clinical presentation, differential diagnosis, evaluation, and treatment of leptospirosis.
Recommended Citation
Cartwright P. Leptospirosis: A review of clinical presentation, evaluation, and management. University of Lynchburg DMSc Doctoral Project Assignment Repository. 2025; 7(3).
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