University of Lynchburg DMSc Doctoral Project Assignment Repository
Specialty
Urology
Advisor
Dr. James Kilgore
Abstract
Overactive bladder (OAB) is a syndrome defined as increased frequency and urgency of urination, and nocturia with or without urge urinary incontinence in the absence of urinary tract infection or other pathology. Standard therapies for OAB include anticholinergic agents, β3-agonists, intravesical botulinum toxin, and percutaneous tibial nerve stimulation (PTNS). The purpose of this paper is to compare OAB treatment modalities and evaluate whether PTNS is an effective treatment for OAB. The significance of PTNS therapy for effectively improving OAB symptoms offers patients who do not tolerate oral medication side effects, or the prohibitive costs of the newer β3-agonists, a safe and effective treatment option. PTNS is an effective treatment for OAB, with fewer side effects than anticholinergic medications. PTNS was applied weekly for 12 weeks, resulting in a reduction in OAB symptoms. Studies have shown a decrease in frequency, urgency, and urge incontinence, with an accompanying improvement in quality of life.
Keywords: overactive bladder, treatments for overactive bladder, percutaneous tibial nerve stimulation
Recommended Citation
Driver JR. Percutaneous Tibial Nerve Stimulation as an Effective Third-Line Therapy for Overactive Bladder: A Comparative Review. University of Lynchburg DMSc Doctoral Project Assignment Repository. 2025; 7(3).
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