University of Lynchburg DMSc Doctoral Project Assignment Repository
Specialty
Cardiothoracic and Vascular Surgery
Advisor
Dr. Thomas Colletti
Abstract
ABSTRACT
Chronic appendicitis is a rare and frequently underrecognized cause of persistent right lower quadrant (RLQ) abdominal pain in adults. Its nonspecific presentation, lack of standardized diagnostic criteria, and overlap with other etiologies often lead to delayed diagnosis, prolonged morbidity, and unnecessary interventions. This report describes a 53-year-old man with a 1-year history of intermittent, dull RLQ pain. Despite normal laboratory tests, endoscopy, colonoscopy, and ultrasonography, symptoms persisted until contrast-enhanced computed tomography revealed subtle appendiceal thickening and an appendicolith. Robotic-assisted laparoscopic appendectomy was performed, with histopathology confirming chronic lymphoplasmacytic infiltration. The patient’s symptoms resolved completely and remained absent at 1-year follow-up. Chronic appendicitis should be considered in adults with unexplained RLQ pain after exclusion of more common etiologies. Normal inflammatory markers and ultrasonography do not rule out appendiceal pathology; advanced imaging and clinical suspicion are essential for diagnosis. Prompt surgical intervention provides clinical relief and diagnostic certainty.
Recommended Citation
Gilcrease C. Chronic Appendicitis in Adults: A Case Report and Literature Review. University of Lynchburg DMSc Doctoral Project Assignment Repository. 2026; 8(1).
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