Student Author Information

Katie HighsmithFollow

Access Type

Open Access

Presentation Type

Oral Presentation

Start Date

April 2019

Department

Biology

Abstract

Blood flow to the tissue of the hands and digits is efficiently regulated by vasoconstriction and vasodilation. Through a series of cadaveric dissection, we examined arteries in the hands and digits, including ulnar artery, radial artery, palmar arteries, and digital arteries, for their distribution (branching) patterns and morphological parameters (e.g., thickness, length between branches, external and internal diameters). Using data directly collected from three female cadavers as input variables to our mathematical model, we simulated vasoconstriction (-20% and -10% diameter) and vasodilation (+10% and +20 diameter) to evaluate the extent of changes in blood volume and flow within the arteries. The most drastic change in blood flow (mm/s) was measured from the ulnar artery to the 2nd digit for both 10% and 20% vasoconstriction ( -21.76 ± 5.40, -54.13 ± 13.57) and vasodilation (15.06 ± 3.68, 25.73 ± 6.24). Our experimental results provide insights into how effective changes in size of blood vessels contribute to regulating blood flow. In addition, our study helps us better understand mechanics of some circulatory disorders, such as Raynaud’s syndrome, that inhibit blood flow to digits due to sudden sympathetic vasospasms.

Faculty Mentor(s)

Dr. Takashi Maie

Rights Statement

The right to download or print any portion of this material is granted by the copyright owner only for personal or educational use. The author/creator retains all proprietary rights, including copyright ownership. Any editing, other reproduction or other use of this material by any means requires the express written permission of the copyright owner. Except as provided above, or for any other use that is allowed by fair use (Title 17, §107 U.S.C.), you may not reproduce, republish, post, transmit or distribute any material from this web site in any physical or digital form without the permission of the copyright owner of the material.

Share

COinS
 
Apr 10th, 2:30 PM

An Anatomical and Functional Analysis of Digital Arteries

Blood flow to the tissue of the hands and digits is efficiently regulated by vasoconstriction and vasodilation. Through a series of cadaveric dissection, we examined arteries in the hands and digits, including ulnar artery, radial artery, palmar arteries, and digital arteries, for their distribution (branching) patterns and morphological parameters (e.g., thickness, length between branches, external and internal diameters). Using data directly collected from three female cadavers as input variables to our mathematical model, we simulated vasoconstriction (-20% and -10% diameter) and vasodilation (+10% and +20 diameter) to evaluate the extent of changes in blood volume and flow within the arteries. The most drastic change in blood flow (mm/s) was measured from the ulnar artery to the 2nd digit for both 10% and 20% vasoconstriction ( -21.76 ± 5.40, -54.13 ± 13.57) and vasodilation (15.06 ± 3.68, 25.73 ± 6.24). Our experimental results provide insights into how effective changes in size of blood vessels contribute to regulating blood flow. In addition, our study helps us better understand mechanics of some circulatory disorders, such as Raynaud’s syndrome, that inhibit blood flow to digits due to sudden sympathetic vasospasms.