Oral Presentations
Location
Room 232, Schewel Hall
Access Type
Open Access
Entry Number
60
Start Date
4-10-2019 2:30 PM
End Date
4-10-2019 2:45 PM
College
Lynchburg College of Arts and Sciences
Department
Biology
Abstract
Blood flow to the tissue of the hands and digits is efficiently regulated by vasoconstriction and vasodilation. Through a series of cadaveric dissection, we examined arteries in the hands and digits, including ulnar artery, radial artery, palmar arteries, and digital arteries, for their distribution (branching) patterns and morphological parameters (e.g., thickness, length between branches, external and internal diameters). Using data directly collected from three female cadavers as input variables to our mathematical model, we simulated vasoconstriction (-20% and -10% diameter) and vasodilation (+10% and +20 diameter) to evaluate the extent of changes in blood volume and flow within the arteries. The most drastic change in blood flow (mm/s) was measured from the ulnar artery to the 2nd digit for both 10% and 20% vasoconstriction ( -21.76 ± 5.40, -54.13 ± 13.57) and vasodilation (15.06 ± 3.68, 25.73 ± 6.24). Our experimental results provide insights into how effective changes in size of blood vessels contribute to regulating blood flow. In addition, our study helps us better understand mechanics of some circulatory disorders, such as Raynaud’s syndrome, that inhibit blood flow to digits due to sudden sympathetic vasospasms.
Faculty Mentor(s)
Dr. Takashi Maie
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Included in
Algebra Commons, Analysis Commons, Cardiovascular Diseases Commons, Cardiovascular System Commons
An Anatomical and Functional Analysis of Digital Arteries
Room 232, Schewel Hall
Blood flow to the tissue of the hands and digits is efficiently regulated by vasoconstriction and vasodilation. Through a series of cadaveric dissection, we examined arteries in the hands and digits, including ulnar artery, radial artery, palmar arteries, and digital arteries, for their distribution (branching) patterns and morphological parameters (e.g., thickness, length between branches, external and internal diameters). Using data directly collected from three female cadavers as input variables to our mathematical model, we simulated vasoconstriction (-20% and -10% diameter) and vasodilation (+10% and +20 diameter) to evaluate the extent of changes in blood volume and flow within the arteries. The most drastic change in blood flow (mm/s) was measured from the ulnar artery to the 2nd digit for both 10% and 20% vasoconstriction ( -21.76 ± 5.40, -54.13 ± 13.57) and vasodilation (15.06 ± 3.68, 25.73 ± 6.24). Our experimental results provide insights into how effective changes in size of blood vessels contribute to regulating blood flow. In addition, our study helps us better understand mechanics of some circulatory disorders, such as Raynaud’s syndrome, that inhibit blood flow to digits due to sudden sympathetic vasospasms.