Triple Negative Infiltrating Ductal Carcinoma in a 34-year-old

Student Author Information

Sunayana Pydah, University of LynchburgFollow

Location

Virtual Recording

Access Type

Campus Access Only

Entry Number

43

Start Date

4-8-2020 12:00 PM

End Date

4-8-2020 1:15 PM

Department

Physician Assistant

Abstract

It is estimated that more than 1 million cases of breast cancer are diagnosed every year worldwide and that breast cancer is responsible for 40,000 deaths annually in the United States^1,2. Triple negative infiltrating ductal carcinoma phenotype comprises 170,000 of these cases diagnosed anually¹. The prevalence of triple negative breast cancer is highest in Caucasian women who are premenopausal.² Additionally, research studies have shown that women with BRCA 1 gene mutations are more likely to have triple negative breast cancer. ² It is important to treat triple negative breast cancer quickly after diagnosis as it is an aggressive form.

Faculty Mentor(s)

Dr. Melissa Shaffron

Comments

References:

1. Anders CK, Carey LA. Biology, metastatic patterns, and treatment of patients with triple-negative breast cancer. Clin Breast Cancer. 2009; 9(suppl 2): S73–S81.

2. Breast Cancer. MD Anderson Cancer Center. Retrieved on 15 Sept 2019 from The University of Texas MD Anderson Cancer Center

3. Lakhani SR, Van De Vijver MJ, Jacquemier J, et al. The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2. J Clin Oncol. 2002;20(9):2310–2318.

Lakhani SR, Van De Vijver MJ, Jacquemier J, et al. The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2. J Clin Oncol. 2002;20(9):2310–2318.

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