Archived Abstracts
Beginning to Characterize the Role of Veillonella Atypica in the Human Microbiome and its Impact on Health
Location
Memorial Ballroom, Hall Campus Center
Access Type
Campus Access Only
Entry Number
22
Start Date
4-8-2020 12:00 PM
End Date
4-8-2020 1:15 PM
Department
Biomedical Science
Abstract
V. atypica is found in many microbiomes of the human body, including the gut and oral cavities. Previous studies have primarily focused on the role of V. atypica in the oral microbiome, its association with periodontal disease, and its role as an early colonizer in the development of dental biofilm. Veillonella atypica is an extremely understudied bacteria that lives in the human microbiome and has known metabolic pathways that utilize lactate as a primary carbon source. Athletes have increased concentrations of lactate in circulation and V. atypica was found to be associated with enhanced athletic performance in endurance athletes. The goal of this study is to learn how to successfully and effectively grow Veillonella atypica in the laboratory and find a link between the prime growth conditions of this bacteria compared to that found in the human body. Our work will include determining how lactate concentration and pH impacts the growth of V. atypica and how these conditions mirror those found in the human body, primarily in athletes.
Faculty Mentor(s)
Dr. Jamie Brooks
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Beginning to Characterize the Role of Veillonella Atypica in the Human Microbiome and its Impact on Health
Memorial Ballroom, Hall Campus Center
V. atypica is found in many microbiomes of the human body, including the gut and oral cavities. Previous studies have primarily focused on the role of V. atypica in the oral microbiome, its association with periodontal disease, and its role as an early colonizer in the development of dental biofilm. Veillonella atypica is an extremely understudied bacteria that lives in the human microbiome and has known metabolic pathways that utilize lactate as a primary carbon source. Athletes have increased concentrations of lactate in circulation and V. atypica was found to be associated with enhanced athletic performance in endurance athletes. The goal of this study is to learn how to successfully and effectively grow Veillonella atypica in the laboratory and find a link between the prime growth conditions of this bacteria compared to that found in the human body. Our work will include determining how lactate concentration and pH impacts the growth of V. atypica and how these conditions mirror those found in the human body, primarily in athletes.