Hunting New Phage Therapy Candidates to Combat Antibiotic Resistant Staphylococcus aureus in the Holy Rivers of India

Location

Room 232, Schewel Hall

Access Type

Campus Access Only

Entry Number

84

Start Date

4-5-2023 10:45 AM

End Date

4-5-2023 11:00 AM

College

Lynchburg College of Arts and Sciences

Department

Biomedical Science

Abstract

Staphylococcus aureus is a potentially deadly bacterium responsible for many kinds of infections, and has displayed multi-drug resistance to antibiotics. Bacteriophages are viruses that infect bacteria and are naturally occurring in the environment, particularly in water, and are a potential weapon in the fight against bacterial infections. This study was conducted to analyze water samples from the Ganges and Yamuna Rivers in India in an attempt to discover new bacteriophages capable of infecting S. aureus. A plaque assay was utilized to determine if bacteriophages were present that were capable of destroying S. aureus bacteria. Isolated bacteriophages will be identified and we will begin to study their potential therapeutic use against clinical multidrug-resistant S. aureus bacterial infections.

Faculty Mentor(s)

Dr. Jamie L. Brooks

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Apr 5th, 10:45 AM Apr 5th, 11:00 AM

Hunting New Phage Therapy Candidates to Combat Antibiotic Resistant Staphylococcus aureus in the Holy Rivers of India

Room 232, Schewel Hall

Staphylococcus aureus is a potentially deadly bacterium responsible for many kinds of infections, and has displayed multi-drug resistance to antibiotics. Bacteriophages are viruses that infect bacteria and are naturally occurring in the environment, particularly in water, and are a potential weapon in the fight against bacterial infections. This study was conducted to analyze water samples from the Ganges and Yamuna Rivers in India in an attempt to discover new bacteriophages capable of infecting S. aureus. A plaque assay was utilized to determine if bacteriophages were present that were capable of destroying S. aureus bacteria. Isolated bacteriophages will be identified and we will begin to study their potential therapeutic use against clinical multidrug-resistant S. aureus bacterial infections.