Date Presented
Spring 4-2006
Document Type
Thesis
Degree Name
Bachelor of Science
Department
Chemistry
First Advisor
Dr. Anne Reeve
Second Advisor
Dr. Priscilla Gannicott
Third Advisor
Dr. Nancy Cowden
Abstract
Aspernigrin A is a compound correlated with inhibiting the growth of cancer cells in the colon. A five-step synthesis was designed for aspernigrin A, projected to yield four intermediates and the final product. The intermediates were analyzed by high field 1HNMR and FT-IR spectroscopy before proceeding to the next step. A model pyridone ring system was successfully prepared from a commercially available pyrone precursor in two steps. These results provide a proof of concept that the synthetic scheme should successfully yield the natural product.
Recommended Citation
Joerger, Erica, "Synthesis of Aspernigrin A" (2006). Undergraduate Theses and Capstone Projects. 64.
https://digitalshowcase.lynchburg.edu/utcp/64