Location
Room 232, Schewel Hall
Access Type
Open Access
Start Date
4-17-2024 9:45 AM
End Date
4-17-2024 10:00 AM
College
Lynchburg College of Arts and Sciences
Department
Biomedical Science
Keywords
LAB, Lactococcus lactis, bacteriocins
Abstract
The human gastrointestinal tract (GIT) harnesses various microbial organisms involved in almost all processes of physiological homeostasis, among these are lactic acid bacteria (LAB). These bacteria, almost all of which belong to the order Lactobacillales, are able to produce lactic acid, and play an important role in food preservation because they produce bacteriocins. Bacteriocins are antimicrobial proteins that are used to fight off related bacteria in their environment that are competing for the same resources. This study focuses on a specific LAB strain, Lactococcus lactis ssp. IL1403 where 21.9% of its predicted genes have not yet been assigned a function. In this study, 12 genes were investigated using a set of bioinformatic tools and databases. Ten were found to have possible functions, and at least 3 of these were found to be related to bacteriocins or their production. Because of the prevalence of bacteriocins in this study, this work can contribute to improving food preservation and preventing microbial growth.
Faculty Mentor(s)
Dr. Christine Terry Dr. Price Blair Professor Stephen Burris
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Included in
Bioinformatics Commons, Biology Commons, Biomedical Informatics Commons, Biotechnology Commons, Cell Anatomy Commons, Food Microbiology Commons, Genetics Commons, Molecular Genetics Commons
Annotation of Hypothetical Genes in Lactococcus lactis ssp. IL403
Room 232, Schewel Hall
The human gastrointestinal tract (GIT) harnesses various microbial organisms involved in almost all processes of physiological homeostasis, among these are lactic acid bacteria (LAB). These bacteria, almost all of which belong to the order Lactobacillales, are able to produce lactic acid, and play an important role in food preservation because they produce bacteriocins. Bacteriocins are antimicrobial proteins that are used to fight off related bacteria in their environment that are competing for the same resources. This study focuses on a specific LAB strain, Lactococcus lactis ssp. IL1403 where 21.9% of its predicted genes have not yet been assigned a function. In this study, 12 genes were investigated using a set of bioinformatic tools and databases. Ten were found to have possible functions, and at least 3 of these were found to be related to bacteriocins or their production. Because of the prevalence of bacteriocins in this study, this work can contribute to improving food preservation and preventing microbial growth.